1sc7: Difference between revisions

Revision as of 01:50, 27 July 2012

1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p

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 [[Image:1sc7.png|left|200px]]
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 {{STRUCTURE_1sc7|  PDB=1sc7  |  SCENE=  }}
 ===Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex===
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 ==See Also==
-*[[Topoisomerase]]
+*[[Topoisomerase|Topoisomerase]]
 ==Reference==
-<ref group="xtra">PMID:15801827</ref><references group="xtra"/>
+<ref group="xtra">PMID:015801827</ref><references group="xtra"/>
 [[Category: DNA topoisomerase]]
 [[Category: Homo sapiens]]
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 [[Category: Drug]]
 [[Category: Idenoisoquinoline]]
+[[Category: Isomerase-dna complex]]
 [[Category: Poison]]
 [[Category: Topoisomerase i]]