3heg: Difference between revisions

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Revision as of 12:23, 28 December 2010

File:3heg.png

Template:STRUCTURE 3heg

P38 in complex with Sorafenib

Template:ABSTRACT PUBMED 20337484

About this Structure

3heg is a 1 chain structure of [[]] with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Namboodiri HV, Bukhtiyarova M, Ramcharan J, Karpusas M, Lee Y, Springman EB. Analysis of imatinib and sorafenib binding to p38alpha compared with c-Abl and b-Raf provides structural insights for understanding the selectivity of inhibitors targeting the DFG-out form of protein kinases. Biochemistry. 2010 May 4;49(17):3611-8. PMID:20337484 doi:10.1021/bi100070r

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