1cza: Difference between revisions

Revision as of 13:17, 28 December 2010

Ligands:

ADP, G6P, GLC

Activity:

Hexokinase, with EC number 2.7.1.1

Related:

1hkb, 1hkc

Structural annotation:
Resources:	CATH : 1Czan02, 1Czan01, 1Czan04, 1Czan03 InterPro : Ipr001312 Pfam : PF00349, PF03727 SCOP : d1czan1, d1czan3, d1czan4, d1czan2 UniProt : P19367

Functional annotation:
Cellular component:	membrane mitochondrion
Biological process:	glycolysis
Molecular function:	nucleotide binding kinase activity catalytic activity transferase activity hexokinase activity ATP binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1cza is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Aleshin AE, Kirby C, Liu X, Bourenkov GP, Bartunik HD, Fromm HJ, Honzatko RB. Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation. J Mol Biol. 2000 Mar 3;296(4):1001-15. PMID:10686099 doi:10.1006/jmbi.1999.3494

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