2rgu: Difference between revisions

Revision as of 15:06, 27 July 2012

2rgu is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin -2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. J Med Chem. 2007 Dec 27;50(26):6450-3. Epub 2007 Dec 1. PMID:18052023 doi:10.1021/jm701280z

@@ Line 1: / Line 1: @@
 [[Image:2rgu.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_2rgu", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_2rgu|  PDB=2rgu  |  SCENE=  }}
 ===Crystal structure of complex of human DPP4 and inhibitor===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_18052023}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 18052023 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_18052023}}
@@ Line 22: / Line 11: @@
 ==See Also==
-*[[Dipeptidyl peptidase]]
+*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
 ==Reference==
-<ref group="xtra">PMID:18052023</ref><references group="xtra"/>
+<ref group="xtra">PMID:018052023</ref><references group="xtra"/>
 [[Category: Dipeptidyl-peptidase IV]]
 [[Category: Homo sapiens]]