2g5t: Difference between revisions

Revision as of 22:19, 26 July 2012

2g5t is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Pei Z, Li X, Longenecker K, von Geldern TW, Wiedeman PE, Lubben TH, Zinker BA, Stewart K, Ballaron SJ, Stashko MA, Mika AK, Beno DW, Long M, Wells H, Kempf-Grote AJ, Madar DJ, McDermott TS, Bhagavatula L, Fickes MG, Pireh D, Solomon LR, Lake MR, Edalji R, Fry EH, Sham HL, Trevillyan JM. Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. J Med Chem. 2006 Jun 15;49(12):3520-35. PMID:16759095 doi:10.1021/jm051283e

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 [[Image:2g5t.png|left|200px]]
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 {{STRUCTURE_2g5t|  PDB=2g5t  |  SCENE=  }}
 ===Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ag===
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 {{ABSTRACT_PUBMED_16759095}}
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 ==See Also==
-*[[Dipeptidyl peptidase]]
+*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
 ==Reference==
-<ref group="xtra">PMID:16759095</ref><references group="xtra"/>
+<ref group="xtra">PMID:016759095</ref><references group="xtra"/>
 [[Category: Dipeptidyl-peptidase IV]]
 [[Category: Homo sapiens]]