3ot8: Difference between revisions

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[[Image:3ot8.png|left|200px]]
[[Image:3ot8.png|left|200px]]


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{{STRUCTURE_3ot8|  PDB=3ot8  |  SCENE=  }}  
{{STRUCTURE_3ot8|  PDB=3ot8  |  SCENE=  }}  


===X-ray crystal structure of compound 17r bound to human Chk1 kinase domain===
===X-ray crystal structure of compound 17r bound to human Chk1 kinase domain===


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{{ABSTRACT_PUBMED_21094608}}
{{ABSTRACT_PUBMED_21094608}}


==About this Structure==
==About this Structure==
[[3ot8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OT8 OCA].  
[[3ot8]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OT8 OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:21094608</ref><references group="xtra"/>
<ref group="xtra">PMID:021094608</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Fischmann, T O.]]
[[Category: Fischmann, T O.]]
[[Category: Kinase]]
[[Category: Phosphatase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 03:33, 26 July 2012

File:3ot8.png

Template:STRUCTURE 3ot8

X-ray crystal structure of compound 17r bound to human Chk1 kinase domain

Template:ABSTRACT PUBMED 21094608

About this Structure

3ot8 is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dwyer MP, Paruch K, Labroli M, Alvarez C, Keertikar KM, Poker C, Rossman R, Fischmann TO, Duca JS, Madison V, Parry D, Davis N, Seghezzi W, Wiswell D, Guzi TJ. Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach-Part 1. Bioorg Med Chem Lett. 2010 Oct 27. PMID:21094608 doi:10.1016/j.bmcl.2010.10.113

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