2xm8: Difference between revisions

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Revision as of 05:09, 12 January 2011

File:2xm8.jpg

Template:STRUCTURE 2xm8

CO-CRYSTAL STRUCTURE OF A SMALL MOLECULE INHIBITOR BOUND TO THE KINASE DOMAIN OF CHK2

Template:ABSTRACT PUBMED 21186793

About this Structure

2xm8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Caldwell JJ, Welsh EJ, Matijssen C, Anderson VE, Antoni L, Boxall K, Urban F, Hayes A, Raynaud FI, Rigoreau LJ, Raynham T, Aherne GW, Pearl LH, Oliver AW, Garrett MD, Collins I. Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2. J Med Chem. 2010 Dec 27. PMID:21186793 doi:10.1021/jm101150b

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