3nba: Difference between revisions

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[[Image:3nba.png|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3nba", creates the "Structure Box" on the page.
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{{STRUCTURE_3nba|  PDB=3nba  |  SCENE=  }}  
{{STRUCTURE_3nba|  PDB=3nba  |  SCENE=  }}  
===Phosphopantetheine Adenylyltranferase from Mycobacterium tuberculosis in complex with adenosine-5'-[(alpha,beta)-methyleno]triphosphate (AMPCPP)===
===Phosphopantetheine Adenylyltranferase from Mycobacterium tuberculosis in complex with adenosine-5'-[(alpha,beta)-methyleno]triphosphate (AMPCPP)===
{{ABSTRACT_PUBMED_20851704}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).  
The line below this paragraph, {{ABSTRACT_PUBMED_20851704}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_20851704}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:20851704</ref><references group="xtra"/>
<ref group="xtra">PMID:020851704</ref><references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Mesecar, A D.]]
[[Category: Mesecar, A D.]]
[[Category: Wubben, T J.]]
[[Category: Wubben, T J.]]
[[Category: Ampcpp]]
[[Category: Phosphopantetheine adenylyltransferase]]
[[Category: Ppat]]
[[Category: Transferase]]
[[Category: Tuberculosis]]

Revision as of 21:15, 17 April 2013

Template:STRUCTURE 3nba

Phosphopantetheine Adenylyltranferase from Mycobacterium tuberculosis in complex with adenosine-5'-[(alpha,beta)-methyleno]triphosphate (AMPCPP)

Template:ABSTRACT PUBMED 20851704

Function

[COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

About this Structure

3nba is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Wubben TJ, Mesecar AD. Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis. J Mol Biol. 2010 Nov 26;404(2):202-19. Epub 2010 Sep 21. PMID:20851704 doi:10.1016/j.jmb.2010.09.002

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