3nlu: Difference between revisions

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[[Image:3nlu.jpg|left|200px]]
[[Image:3nlu.png|left|200px]]


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{{STRUCTURE_3nlu|  PDB=3nlu  |  SCENE=  }}  
{{STRUCTURE_3nlu|  PDB=3nlu  |  SCENE=  }}  


===Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===
===Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===


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{{ABSTRACT_PUBMED_20843082}}
{{ABSTRACT_PUBMED_20843082}}


==About this Structure==
==About this Structure==
[[3nlu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLU OCA].  
[[3nlu]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLU OCA].  
 
==See Also==
*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20843082</ref><references group="xtra"/>
<ref group="xtra">PMID:020843082</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
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[[Category: Silverman, R B.]]
[[Category: Silverman, R B.]]
[[Category: Xue, F.]]
[[Category: Xue, F.]]
[[Category: Heme enzyme]]
[[Category: Nitric oxide synthase]]
[[Category: Oxidoreductase]]
[[Category: Substrate inhibitor]]

Revision as of 06:07, 26 July 2012

File:3nlu.png

Template:STRUCTURE 3nlu

Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlu is a 2 chain structure of Nitric Oxide Synthase with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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