3nlv: Difference between revisions

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Revision as of 06:23, 19 January 2011

File:3nlv.jpg

Template:STRUCTURE 3nlv

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlv is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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