3nlv: Difference between revisions

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[[Image:3nlv.jpg|left|200px]]
[[Image:3nlv.png|left|200px]]


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{{STRUCTURE_3nlv|  PDB=3nlv  |  SCENE=  }}  
{{STRUCTURE_3nlv|  PDB=3nlv  |  SCENE=  }}  


===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine===
===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine===


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{{ABSTRACT_PUBMED_20843082}}
{{ABSTRACT_PUBMED_20843082}}


==About this Structure==
==About this Structure==
[[3nlv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLV OCA].  
[[3nlv]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLV OCA].  
 
==See Also==
*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:20843082</ref><references group="xtra"/>
<ref group="xtra">PMID:020843082</ref><references group="xtra"/>
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Li, H.]]
[[Category: Li, H.]]
[[Category: Poulos, T L.]]
[[Category: Poulos, T L.]]
[[Category: Heme thiolate enzyme]]
[[Category: Inhibitor]]
[[Category: Nitric oxide synthase]]
[[Category: Oxidoreductase]]

Revision as of 15:36, 27 July 2012

File:3nlv.png

Template:STRUCTURE 3nlv

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlv is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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