A Disintegrin And Metalloproteinase: Difference between revisions
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New page: left|200px|thumb|Crystal structure of A Disintegrin And Metalloproteinase [[2ao7]] {{STRUCTURE_2ao7| PDB=2ao7 | SIZE=300| SCENE= |right|CAPTION=A Disintegrin And Metal... |
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[[Image:2ao7.png|left|200px|thumb|Crystal structure of A Disintegrin And Metalloproteinase [[2ao7]]]] | [[Image:2ao7.png|left|200px|thumb|Crystal structure of A Disintegrin And Metalloproteinase [[2ao7]]]] | ||
{{STRUCTURE_2ao7| PDB=2ao7 | SIZE=300| SCENE= |right|CAPTION=A Disintegrin And Metalloproteinase [[2ao7]] }} | {{STRUCTURE_2ao7| PDB=2ao7 | SIZE=300| SCENE=A_Disintegrin_And_Metalloproteinase/Cv/1 |right|CAPTION=A Disintegrin And Metalloproteinase [[2ao7]] }} | ||
[[A Disintegrin And Metalloproteinase]] (ADAM) are peptidases which cleave off extracellular portions of transmembrane proteins. ADAM inhibitors are used in anti-cancer therapy. ADAM family members are numbered. ADAM10 cleaves ephrin. ADAM17 processes the tumor necrosis factor-α. ADAM33 is implicated in asthma. The images at the left and at the right correspond to one representative ADAM, ''i.e.'' the crystal structure of bovine A Disintegrin And Metalloproteinase 10 ([[2ao7]]). | [[A Disintegrin And Metalloproteinase]] (ADAM) are peptidases which cleave off extracellular portions of transmembrane proteins. ADAM inhibitors are used in anti-cancer therapy. ADAM family members are numbered. ADAM10 cleaves ephrin. ADAM17 processes the tumor necrosis factor-α. ADAM33 is implicated in asthma. The images at the left and at the right correspond to one representative ADAM, ''i.e.'' the crystal structure of bovine A Disintegrin And Metalloproteinase 10 ([[2ao7]]). | ||
