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== '''Introduction''' == | |||
Ribonuclease A is an enzyme involved in catalyzing RNA degradation. The structure of RNase A has been determined through crystallization and FABMS. There are several features of its structure that are pertinent to its folding and function. The catalytic residues of RNase A include His12, His 119, and Lys41. The active site lies within its cleft. RNase A has eight cysteine residues present that form four disulfide linkages which contribute to the ordered structure that has been observed as well as the speed of folding. Another important aspect to folding is the presence of two ''cis'' proline residues. | |||
