TolQ: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
TolQ is a polytopic protein located in the inner (cytoplasmic) membrane. It contains approximately 230 amino acids and is important in the maintenance of the bacterial envelope integrity as well as the import of filamentous bacteriophage and group A colicins. <ref>PMID: 8300535</ref> | TolQ is a polytopic protein located in the inner (cytoplasmic) membrane. It contains approximately 230 amino acids and is important in the maintenance of the bacterial envelope integrity as well as the import of filamentous bacteriophage and group A colicins. <ref name='Vianney'>PMID: 8300535</ref> | ||
==Structure== | ==Structure== | ||
| Line 6: | Line 6: | ||
[[Image:TolQ.jpg|400px|right|thumb| The TolQ Membrane-spanning domains <ref>PMID: 8662905</ref>]] | [[Image:TolQ.jpg|400px|right|thumb| The TolQ Membrane-spanning domains <ref>PMID: 8662905</ref>]] | ||
It has been shown that 4 to 6 TolQ molecules associate in the TolQRA complex, and that they form multimers which interact with the transmembrane helices (TMH) of TolQ, TolR and TolA <ref>PMID: 21285349</ref>. The multimers are formed by the three TMHs <ref>PMID: 8300535</ref> of TolQ, the last of which undergo a conformational change to form a hairpin, while the first TMH forms an intermolecular interaction | It has been shown that 4 to 6 TolQ molecules associate in the TolQRA complex, and that they form multimers which interact with the transmembrane helices (TMH) of TolQ, TolR and TolA <ref>PMID: 21285349</ref>. The multimers are formed by the three TMHs <ref name='Vianney>PMID: 8300535</ref> of TolQ, the last of which undergo a conformational change to form a hairpin, while the first TMH forms an intermolecular interaction | ||
==To view related Tol entries see:== | ==To view related Tol entries see:== | ||
