3ps3: Difference between revisions

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[[Image:3ps3.png|left|200px]]
<!--
The line below this paragraph, containing "STRUCTURE_3ps3", creates the "Structure Box" on the page.
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{{STRUCTURE_3ps3|  PDB=3ps3  |  SCENE=  }}  
{{STRUCTURE_3ps3|  PDB=3ps3  |  SCENE=  }}  
===Crystal structure of the Escherichia Coli LPXC/LPC-053 complex===
===Crystal structure of the Escherichia Coli LPXC/LPC-053 complex===
{{ABSTRACT_PUBMED_21194954}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/D5CV28_ECOKI D5CV28_ECOKI]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]
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{{ABSTRACT_PUBMED_21194954}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21194954</ref><references group="xtra"/>
<ref group="xtra">PMID:021194954</ref><references group="xtra"/><references/>
[[Category: Escherichia coli ihe3034]]
[[Category: Escherichia coli ihe3034]]
[[Category: Lee, C J]]
[[Category: Lee, C J]]
[[Category: Zhou, P.]]
[[Category: Zhou, P.]]
[[Category: Acyl udp-glcnac]]
[[Category: Antibiotic]]
[[Category: Baab sandwich]]
[[Category: Deacetylation]]
[[Category: Hydrolase]]
[[Category: Hydrolase-antibiotic complex]]
[[Category: Hydroxamate]]
[[Category: Lipid a biosynthesis]]
[[Category: Lipid a synthesis]]
[[Category: Lpc-053]]
[[Category: Lpxc]]

Revision as of 08:34, 8 May 2013

Template:STRUCTURE 3ps3

Crystal structure of the Escherichia Coli LPXC/LPC-053 complex

Template:ABSTRACT PUBMED 21194954

Function

[D5CV28_ECOKI] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]

About this Structure

3ps3 is a 1 chain structure with sequence from Escherichia coli ihe3034. Full crystallographic information is available from OCA.

Reference

  1. Liang X, Lee CJ, Chen X, Chung HS, Zeng D, Raetz CR, Li Y, Zhou P, Toone EJ. Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. Bioorg Med Chem. 2011 Jan 15;19(2):852-60. Epub 2010 Dec 9. PMID:21194954 doi:10.1016/j.bmc.2010.12.017

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