3ml6: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "3ml6" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3ml6| PDB=3ml6 | SCENE= }} | {{STRUCTURE_3ml6| PDB=3ml6 | SCENE= }} | ||
===a complex between Dishevlled2 and clathrin adaptor AP-2=== | ===a complex between Dishevlled2 and clathrin adaptor AP-2=== | ||
{{ABSTRACT_PUBMED_20947020}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DVL2_MOUSE DVL2_MOUSE]] Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes.<ref>PMID:17199046</ref> <ref>PMID:21189423</ref> <ref>PMID:20947020</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ml6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3ml6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ML6 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020947020</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: Harrison, S C.]] | [[Category: Harrison, S C.]] | ||
[[Category: Kirchhausen, T L.]] | [[Category: Kirchhausen, T L.]] | ||
[[Category: Xing, Y.]] | [[Category: Xing, Y.]] | ||
[[Category: Yu, A.]] | [[Category: Yu, A.]] | ||
[[Category: Ap2]] | |||
[[Category: Dishevelled]] | |||
[[Category: Frizzled internalization]] | |||
[[Category: Non-canonical wnt signaling]] | |||
[[Category: Protein transport]] | |||