3q4c: Difference between revisions
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[[Image:3q4c.jpg|left|200px]] | |||
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{{STRUCTURE_3q4c| PDB=3q4c | SCENE= }} | |||
===Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292=== | |||
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{{ABSTRACT_PUBMED_19371126}} | |||
==About this Structure== | |||
[[3q4c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q4C OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19371126</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Marmorstein, R.]] | |||
[[Category: Meggers, E.]] | |||
[[Category: Pagano, N.]] | |||
[[Category: Pregman, H.]] | |||
[[Category: Qin, J.]] | |||
[[Category: Streu, C.]] | |||
[[Category: Xie, P.]] | |||
Revision as of 06:58, 2 March 2011
Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292
Template:ABSTRACT PUBMED 19371126
About this Structure
3q4c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 2009 Jun 16;48(23):5187-98. PMID:19371126 doi:10.1021/bi802067u