3pp1: Difference between revisions

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Revision as of 09:59, 23 February 2011

File:3pp1.jpg

Template:STRUCTURE 3pp1

Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP

Template:ABSTRACT PUBMED 21310613

About this Structure

3pp1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Dong Q, Dougan DR, Gong X, Halkowycz P, Jin B, Kanouni T, O'Connell SM, Scorah N, Shi L, Wallace MB, Zhou F. Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1315-9. Epub 2011 Jan 22. PMID:21310613 doi:10.1016/j.bmcl.2011.01.071

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