3qk3: Difference between revisions
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{{STRUCTURE_3qk3| PDB=3qk3 | SCENE= }} | {{STRUCTURE_3qk3| PDB=3qk3 | SCENE= }} | ||
===Crystal structure of human beta-crystallin B3=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Non-syndromic congenital cataract. Cataract, congenital, nuclear, autosomal recessive 2 (CATCN2) [MIM:[http://omim.org/entry/609741 609741]]: A congenital cataract affecting the central nucleus of the eye. Nucler cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:15914629</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Crystallins are the dominant structural components of the vertebrate eye lens. | |||
==About this Structure== | ==About this Structure== | ||
[[3qk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. | [[3qk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
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[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
[[Category: Yue, W W.]] | [[Category: Yue, W W.]] | ||
[[Category: Beta b3]] | |||
[[Category: Cataract]] | |||
[[Category: Crybb3]] | |||
[[Category: Crystallin]] | |||
[[Category: Eye lens protein]] | |||
[[Category: Sgc]] | |||
[[Category: Structural genomic]] | |||
[[Category: Structural genomics consortium]] | |||
[[Category: Structural protein]] | |||