3ime: Difference between revisions
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{{STRUCTURE_3ime| PDB=3ime | SCENE= }} | {{STRUCTURE_3ime| PDB=3ime | SCENE= }} | ||
===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.40 Ang resolution in complex with fragment compound 1-Benzofuran-2-carboxylic acid=== | ===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.40 Ang resolution in complex with fragment compound 1-Benzofuran-2-carboxylic acid=== | ||
==About this Structure== | ==About this Structure== | ||
[[3ime]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IME OCA]. | [[3ime]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IME OCA]. | ||
==See Also== | |||
*[[Pantothenate synthetase|Pantothenate synthetase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019780086</ref><references group="xtra"/> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
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[[Category: Silvestre, H L.]] | [[Category: Silvestre, H L.]] | ||
[[Category: Wen, S.]] | [[Category: Wen, S.]] | ||
[[Category: Atp-binding]] | |||
[[Category: Drug design]] | |||
[[Category: Enzyme]] | |||
[[Category: Fragment-based]] | |||
[[Category: Ligase]] | |||
[[Category: Magnesium]] | |||
[[Category: Metal-binding]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Pantothenate biosynthesis]] | |||
Revision as of 10:56, 13 March 2013
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 2.40 Ang resolution in complex with fragment compound 1-Benzofuran-2-carboxylic acid
About this Structure
3ime is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821
