Atropine: Difference between revisions

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In addition to its ability to form complexes with acetylcholine receptors, atropine can also complex with phospholipase A2. Phospholipase A2 is a category of heat-stable enzymes which are involved in cell signaling processes, such as the inflammatory response <ref>Kumar, Jainendra; Bala, Priti; Vihwal, Preeti. ''Analysis of Interaction of atropine with phospholipase A2 (1th6.pdb)''. Department of Botany and Biotechnlogy, College of Commerce, Patna, India.</ref>.
In addition to its ability to form complexes with acetylcholine receptors, atropine can also complex with phospholipase A2. Phospholipase A2 is a category of heat-stable enzymes which are involved in cell signaling processes, such as the inflammatory response <ref>Kumar, Jainendra; Bala, Priti; Vihwal, Preeti. ''Analysis of Interaction of atropine with phospholipase A2 (1th6.pdb)''. Department of Botany and Biotechnlogy, College of Commerce, Patna, India.</ref>.


Atropine can be seen in complex with phospholipase 2A on the right. The <scene name='Sandbox_53/side-chain residues/1'>side-chain residues</scene> of phospholipase A in the active site can be seen when zooming in on the protein to the right.  
Atropine can be seen in complex with phospholipase 2A on the right. The <scene name='Sandbox_53/Atropine_structure/1'>structure of atropine</scene> can be seen more clearly in gray using the ball-and stick representation of the drug and protein.
 
Atropine interacts with phospholipase 2A at residues asp29 and tyr49 on the protein. The (interactions) of atropine with phospholipase 2A can be seen on the right. the amino acid residues in the active site are labeled.  


== '''References''' ==
== '''References''' ==