Sandbox 55: Difference between revisions

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==Structure and Synthesis==
==Structure and Synthesis==
 
[[Image:Lipitor.jpg]]
When synthesizing a statin, four properties need to be taken into consideration: high affinity for the HMG-CoA reductase active site, selective uptake into hepatic cells instead of non-hepatic cells, low endogenous inhibitory equivalents, and a relatively long half-life/duration of effect.  
When synthesizing a statin, four properties need to be taken into consideration: high affinity for the HMG-CoA reductase active site, selective uptake into hepatic cells instead of non-hepatic cells, low endogenous inhibitory equivalents, and a relatively long half-life/duration of effect.  


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<references/>
<references/>
[[Image:[[Image:Example.jpg]][[Image:Example.jpg]]]]