Sandbox 55: Difference between revisions
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==Structure and Synthesis== | ==Structure and Synthesis== | ||
[[Image:Lipitor.jpg]] | |||
When synthesizing a statin, four properties need to be taken into consideration: high affinity for the HMG-CoA reductase active site, selective uptake into hepatic cells instead of non-hepatic cells, low endogenous inhibitory equivalents, and a relatively long half-life/duration of effect. | When synthesizing a statin, four properties need to be taken into consideration: high affinity for the HMG-CoA reductase active site, selective uptake into hepatic cells instead of non-hepatic cells, low endogenous inhibitory equivalents, and a relatively long half-life/duration of effect. | ||
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[[Image:[[Image:Example.jpg]][[Image:Example.jpg]]]] | |||