Alendronate: Difference between revisions

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== '''Fosamax (Alendronate)''' ==
== '''Alendronate (Fosamax®)''' ==
basic info here
 
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Alendronate is a bisphosphonate used to treat and prevent osteoporosis in postmenopausal women and in men.<ref>http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000018/</ref>


== History ==
== History ==
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<scene name='Sandbox_59/Active_site_ligand_space_fill/2'>space fill active site with bound ligand</scene>
<scene name='Sandbox_59/Active_site_ligand_space_fill/2'>space fill active site with bound ligand</scene>


<scene name='Sandbox_59/Fpps_bound_phosphate/1'>FPPS bound phosphate</scene>
<scene name='Sandbox_59/Fpps_bound_phosphate/2'>FPPS bound phosphate</scene>


<scene name='Sandbox_59/Fpps_space_fill/1'>FPPS cleft</scene>
<scene name='Sandbox_59/Fpps_hydrophobic/1'>hydrphobic FPPS</scene>


<scene name='Sandbox_59/Fpps/2'>FPPS</scene>
<scene name='Sandbox_59/Fpps/2'>FPPS</scene>
<Structure load='2f92' size='500' frame='true' align='right' caption='FPPS Asymmetric unit' scene='Insert optional scene name here' />
<Structure load='2f92' size='500' frame='true' align='right' caption='FPPS Asymmetric unit' scene='Insert optional scene name here' />




== Side affects of Drug ==
== Side affects of Drug ==
<references/>

Revision as of 04:05, 11 March 2011

Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.

Alendronate (Fosamax®)


Alendronate is a bisphosphonate used to treat and prevent osteoporosis in postmenopausal women and in men.[1]

History

Structure

Target Protein

Bound Alendronate

active site with bound ligand

space fill active site with bound ligand

FPPS bound phosphate

hydrphobic FPPS

FPPS

FPPS Asymmetric unit

Drag the structure with the mouse to rotate


Side affects of Drug

Proteopedia Page Contributors and Editors (what is this?)

Anne Goodling, OCA, David Canner, Justin Myles Kidd