Alendronate: Difference between revisions
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== History of Bisphosphonates == | == History of Bisphosphonates == | ||
Bisphosphonates were first synthesized in Germany in 1865, but were not studied biologically until 1968. In the interim time, they were used in the textile and fertilizer industries due to their apparent inhibitory effect on calcium carbonate. However, in 1968, a group in Switzerland discovered bisphosphonates in humans after finding inorganic pyrophosphates which inhibited calcium phosphate precipitate in urine and plasma.<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC138713/?tool=pmcentrez</ref> | |||
== Structure == | == Structure == | ||
