Sandbox 80: Difference between revisions
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=Saquinavir= | =Saquinavir= | ||
This is an antiviral drug used to treat HIV by inhibiting proteases in the virus. This inhibition causes the spread of the virus to decrease significantly. The protease | This is an antiviral drug used to treat HIV by inhibiting proteases in the virus. This inhibition causes the spread of the virus to decrease significantly. The <scene name='Sandbox_80/Protease/1'>protease</scene> is an enzyme that the virus uses to produce the proteins necessary to assemble more viruses. | ||
Revision as of 08:26, 11 March 2011
Template:Tims Sandbox Reservation
This is an antiviral drug used to treat HIV by inhibiting proteases in the virus. This inhibition causes the spread of the virus to decrease significantly. The protease is an enzyme that the virus uses to produce the proteins necessary to assemble more viruses.
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| 3oxc, resolution 1.16Å (default scene) | |||||||||||||
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| Ligands: | FMT, ROC, SO4 | ||||||||||||
| Gene: | pol (Human immunodeficiency virus 1) | ||||||||||||
| Activity: | HIV-1 retropepsin, with EC number 3.4.23.16 | ||||||||||||
| Related: | 2ien, 3mws, 3nu3, 3cyx, 3d1x, 3d1y, 2nmy, 2nmz, 2nnk, 2nnp | ||||||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Structure
The chemical formula of Saquinavir is (C39)(H54)(N6)(O8)S and the molecular weight is 766.94 g/mol. This compound is
