1oit: Difference between revisions

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[[Image:1oit.png|left|200px]]
[[Image:1oit.png|left|200px]]


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{{STRUCTURE_1oit|  PDB=1oit  |  SCENE=  }}  
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===IMIDAZOPYRIDINES: A POTENT AND SELECTIVE CLASS OF CYCLIN-DEPENDENT KINASE INHIBITORS IDENTIFIED THROUGH STRUCTURE-BASED HYBRIDISATION===
===IMIDAZOPYRIDINES: A POTENT AND SELECTIVE CLASS OF CYCLIN-DEPENDENT KINASE INHIBITORS IDENTIFIED THROUGH STRUCTURE-BASED HYBRIDISATION===


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==See Also==
==See Also==
*[[Cell Division Protein Kinase 2]]
*[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]]


==Reference==
==Reference==
<ref group="xtra">PMID:12941325</ref><ref group="xtra">PMID:8917641</ref><references group="xtra"/>
<ref group="xtra">PMID:012941325</ref><ref group="xtra">PMID:008917641</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]

Revision as of 20:16, 26 July 2012

File:1oit.png

Template:STRUCTURE 1oit

IMIDAZOPYRIDINES: A POTENT AND SELECTIVE CLASS OF CYCLIN-DEPENDENT KINASE INHIBITORS IDENTIFIED THROUGH STRUCTURE-BASED HYBRIDISATION

Template:ABSTRACT PUBMED 12941325

About this Structure

1oit is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Anderson M, Beattie JF, Breault GA, Breed J, Byth KF, Culshaw JD, Ellston RP, Green S, Minshull CA, Norman RA, Pauptit RA, Stanway J, Thomas AP, Jewsbury PJ. Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3021-6. PMID:12941325
  2. Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a

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