Sandbox CsrA: Difference between revisions
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The ''Vibrio'' structure described in this section was determined [[theoretical models|theoretically]], and hence should be interpreted with caution.</td></tr></table> | The ''Vibrio'' structure described in this section was determined [[theoretical models|theoretically]], and hence should be interpreted with caution.</td></tr></table> | ||
<Structure load='1vpz' size='500' frame='true' align='right' caption='CsRA structures aligned' scene='Sandbox_CsrA/Structuresplusmodel/5' /> | <Structure load='1vpz' size='500' frame='true' align='right' caption='CsRA structures aligned' scene='Sandbox_CsrA/Structuresplusmodel/5' /> | ||
{{Template:Checkbox Toggle CsrRNABinding}} | {{Template:Checkbox Toggle CsrRNABinding}} | ||
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{{Template:Checkbox Toggle Model2Cartoon}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br> | {{Template:Checkbox Toggle Model2Cartoon}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br> | ||
{{Template:Checkbox Toggle Model3Cartoon}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br> | {{Template:Checkbox Toggle Model3Cartoon}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br> | ||
{{Template:Checkbox Toggle Model4Cartoon}} (<font color=" | {{Template:Checkbox Toggle Model4Cartoon}} (<font color="magenta">'''Vibrio fischeri'''</font>)<br> | ||
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{{Template:Checkbox Toggle Model2BackboneTrace}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br> | {{Template:Checkbox Toggle Model2BackboneTrace}} (<font color="pink">'''Pseudomonas aeruginosa'''</font>)<br> | ||
{{Template:Checkbox Toggle Model3BackboneTrace}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br> | {{Template:Checkbox Toggle Model3BackboneTrace}} (<font color="wheat">'''Yersinia enterocolitica'''</font>)<br> | ||
{{Template:Checkbox Toggle Model4BackboneTrace}} (<font color=" | {{Template:Checkbox Toggle Model4BackboneTrace}} (<font color="magenta">'''Vibrio fischeri'''</font>)<br> | ||
Latest revision as of 15:59, 14 March 2011
CsrA
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Residues 24-27 form a putative RNA-binding motif[1].
Residues Highlighted by Alanine Scanning Mutation of CsrA[2]
E. coli CsrA
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Residues Highlighted by Alanine Scanning Mutation of CsrA[2]
Aligned CsrA structures
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Residues Highlighted by Alanine Scanning Mutation of CsrA[2]
Aligned Structures
Display cartoon representation of aligned CsrA structures.
(E. coli)
(Pseudomonas aeruginosa)
(Yersinia enterocolitica)
Display backbone trace of aligned CsrA structures.
(E. coli)
(Pseudomonas aeruginosa)
(Yersinia enterocolitica)
Model of Vibrio CsrA
 |
|
Residues Highlighted by Alanine Scanning Mutation of CsrA[2]
Aligned CsrA structures and Vibrio Model
|
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Residues Highlighted by Alanine Scanning Mutation of CsrA[2]
Aligned Structures
Display cartoon representation of aligned CsrA structures.
(E. coli)
(Pseudomonas aeruginosa)
(Yersinia enterocolitica)
(Vibrio fischeri)
Display backbone trace of aligned CsrA structures.
(E. coli)
(Pseudomonas aeruginosa)
(Yersinia enterocolitica)
(Vibrio fischeri)
Structures Used On This Page
1y00 is a 2 chains structure of sequences from Escherichia coli. Full experimental information is available from OCA.
1vpz is a 2 chains structure of sequences from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
2bti is a 2 chains structure of sequences from Yersinia enterocolitica. Full crystallographic information is available from OCA.
See Also
1t3o - NMR structure of Bacillus subtilis CsrA
References
- ↑ Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Jaroszewski L, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, Miller MD, Moy K, Nigoghossian E, Paulsen J, Quijano K, Reyes R, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA. Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 A resolution reveals a new fold. Proteins. 2005 Nov 1;61(2):449-53. PMID:16104018 doi:10.1002/prot.20502
- ↑ 2.0 2.1 2.2 2.3 2.4 Mercante J, Suzuki K, Cheng X, Babitzke P, Romeo T. Comprehensive alanine-scanning mutagenesis of Escherichia coli CsrA defines two subdomains of critical functional importance. J Biol Chem. 2006 Oct 20;281(42):31832-42. Epub 2006 Aug 21. PMID:16923806 doi:10.1074/jbc.M606057200
