3caj: Difference between revisions
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[[Image:3caj.png|left|200px]] | [[Image:3caj.png|left|200px]] | ||
{{STRUCTURE_3caj| PDB=3caj | SCENE= }} | {{STRUCTURE_3caj| PDB=3caj | SCENE= }} | ||
===Crystal structure of the human carbonic anhydrase II in complex with ethoxzolamide=== | ===Crystal structure of the human carbonic anhydrase II in complex with ethoxzolamide=== | ||
{{ABSTRACT_PUBMED_18359629}} | {{ABSTRACT_PUBMED_18359629}} | ||
==About this Structure== | ==About this Structure== | ||
[[3caj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAJ OCA]. | [[3caj]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAJ OCA]. | ||
==See Also== | |||
*[[Carbonic anhydrase|Carbonic anhydrase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018359629</ref><ref group="xtra">PMID:008142888</ref><ref group="xtra">PMID:009541386</ref><references group="xtra"/> | ||
[[Category: Carbonate dehydratase]] | [[Category: Carbonate dehydratase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fiore, A Di.]] | [[Category: Fiore, A Di.]] | ||
[[Category: Simone, G De.]] | [[Category: Simone, G De.]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
Revision as of 06:50, 26 July 2012
Crystal structure of the human carbonic anhydrase II in complex with ethoxzolamide
Template:ABSTRACT PUBMED 18359629
About this Structure
3caj is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Di Fiore A, Pedone C, Antel J, Waldeck H, Witte A, Wurl M, Scozzafava A, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2669-74. Epub 2008 Mar 18. PMID:18359629 doi:10.1016/j.bmcl.2008.03.023
- Smith GM, Alexander RS, Christianson DW, McKeever BM, Ponticello GS, Springer JP, Randall WC, Baldwin JJ, Habecker CN. Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors. Protein Sci. 1994 Jan;3(1):118-25. PMID:8142888
- Stams T, Chen Y, Boriack-Sjodin PA, Hurt JD, Liao J, May JA, Dean T, Laipis P, Silverman DN, Christianson DW. Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination. Protein Sci. 1998 Mar;7(3):556-63. PMID:9541386 doi:10.1002/pro.5560070303
