1e2k: Difference between revisions

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[[Image:1e2k.png|left|200px]]
[[Image:1e2k.png|left|200px]]


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{{STRUCTURE_1e2k|  PDB=1e2k  |  SCENE=  }}  
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===KINETICS AND CRYSTAL STRUCTURE OF THE WILD-TYPE AND THE ENGINEERED Y101F MUTANT OF HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (NORTH)-METHANOCARBA-THYMIDINE===
===KINETICS AND CRYSTAL STRUCTURE OF THE WILD-TYPE AND THE ENGINEERED Y101F MUTANT OF HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (NORTH)-METHANOCARBA-THYMIDINE===


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{{ABSTRACT_PUBMED_10924157}}
{{ABSTRACT_PUBMED_10924157}}


==About this Structure==
==About this Structure==
[[1e2k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Herpes_simplex_virus_(type_1/_strain_17) Herpes simplex virus (type 1/ strain 17)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2K OCA].  
[[1e2k]] is a 2 chain structure of [[Thymidine kinase]] with sequence from [http://en.wikipedia.org/wiki/Herpes_simplex_virus_(type_1/_strain_17) Herpes simplex virus (type 1/ strain 17)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E2K OCA].  
 
==See Also==
*[[Thymidine kinase|Thymidine kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:10924157</ref><ref group="xtra">PMID:7628623</ref><ref group="xtra">PMID:7552712</ref><references group="xtra"/>
<ref group="xtra">PMID:010924157</ref><ref group="xtra">PMID:007628623</ref><ref group="xtra">PMID:007552712</ref><references group="xtra"/>
[[Category: Thymidine kinase]]
[[Category: Thymidine kinase]]
[[Category: Scapozza, L.]]
[[Category: Scapozza, L.]]
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[[Category: Thymidine kinase]]
[[Category: Thymidine kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: X-ray structure]]

Revision as of 04:29, 27 July 2012

File:1e2k.png

Template:STRUCTURE 1e2k

KINETICS AND CRYSTAL STRUCTURE OF THE WILD-TYPE AND THE ENGINEERED Y101F MUTANT OF HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (NORTH)-METHANOCARBA-THYMIDINE

Template:ABSTRACT PUBMED 10924157

About this Structure

1e2k is a 2 chain structure of Thymidine kinase with sequence from Herpes simplex virus (type 1/ strain 17). Full crystallographic information is available from OCA.

See Also

Reference

  1. Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L. Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine. Biochemistry. 2000 Aug 8;39(31):9597-603. PMID:10924157
  2. Wild K, Bohner T, Aubry A, Folkers G, Schulz GE. The three-dimensional structure of thymidine kinase from herpes simplex virus type 1. FEBS Lett. 1995 Jul 17;368(2):289-92. PMID:7628623
  3. Brown DG, Visse R, Sandhu G, Davies A, Rizkallah PJ, Melitz C, Summers WC, Sanderson MR. Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir. Nat Struct Biol. 1995 Oct;2(10):876-81. PMID:7552712

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