2f32: Difference between revisions

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Revision as of 21:20, 14 March 2011

File:2f32.png

Template:STRUCTURE 2f32

Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium

Template:ABSTRACT PUBMED 16600969

About this Structure

2f32 is a 1 chain structure with sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.

Reference

  1. Yousef MS, Bischoff N, Dyer CM, Baase WA, Matthews BW. Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme. Protein Sci. 2006 Apr;15(4):853-61. PMID:16600969 doi:15/4/853
  2. Yousef MS, Baase WA, Matthews BW. Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11583-6. Epub 2004 Jul 30. PMID:15286283 doi:10.1073/pnas.0404482101
  3. Sagermann M, Baase WA, Matthews BW. Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6078-83. PMID:10339544
  4. Sagermann M, Gay L, Matthews BW. Long-distance conformational changes in a protein engineered by modulated sequence duplication. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9191-5. Epub 2003 Jul 17. PMID:12869697 doi:10.1073/pnas.1633549100

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