2v4h: Difference between revisions

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[[Image:2v4h.png|left|200px]]
[[Image:2v4h.png|left|200px]]


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{{STRUCTURE_2v4h|  PDB=2v4h  |  SCENE=  }}  
{{STRUCTURE_2v4h|  PDB=2v4h  |  SCENE=  }}  


===NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX===
===NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX===


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{{ABSTRACT_PUBMED_19854204}}


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==Reference==
==Reference==
<ref group="xtra">PMID:19854204</ref><ref group="xtra">PMID:17766391</ref><references group="xtra"/>
<ref group="xtra">PMID:019854204</ref><ref group="xtra">PMID:017766391</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Agou, F.]]
[[Category: Agou, F.]]
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[[Category: Haouz, A.]]
[[Category: Haouz, A.]]
[[Category: Veron, M.]]
[[Category: Veron, M.]]
[[Category: Coiled coil]]
[[Category: Cytoplasm]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Nemo - ikk gamma - nfkb pathway - darpin]]
[[Category: Nemo - ikk gamma - nfkb pathway -darpin]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Ubl conjugation]]
[[Category: Zinc]]
[[Category: Zinc-finger]]

Revision as of 13:15, 30 January 2013

File:2v4h.png

Template:STRUCTURE 2v4h

NEMO CC2-LZ DOMAIN - 1D5 DARPIN COMPLEX

Template:ABSTRACT PUBMED 19854204

About this Structure

2v4h is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Grubisha O, Kaminska M, Duquerroy S, Fontan E, Cordier F, Haouz A, Raynal B, Chiaravalli J, Delepierre M, Israel A, Veron M, Agou F. DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding. J Mol Biol. 2010 Jan 8;395(1):89-104. Epub 2009 Oct 23. PMID:19854204 doi:10.1016/j.jmb.2009.10.018
  2. Wyler E, Kaminska M, Coic YM, Baleux F, Veron M, Agou F. Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO. Protein Sci. 2007 Sep;16(9):2013-22. PMID:17766391 doi:16/9/2013

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