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[[Image:2bkl.png|left|200px]]
[[Image:2bkl.png|left|200px]]


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===STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY===
===STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY===


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{{ABSTRACT_PUBMED_15738423}}


==About this Structure==
==About this Structure==
[[2bkl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKL OCA].  
[[2bkl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myxococcus_xanthus Myxococcus xanthus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKL OCA].  
==See Also==
*[[Prolyl Endopeptidase|Prolyl Endopeptidase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15738423</ref><ref group="xtra">PMID:15245330</ref><ref group="xtra">PMID:12351792</ref><ref group="xtra">PMID:11915948</ref><references group="xtra"/>
<ref group="xtra">PMID:015738423</ref><ref group="xtra">PMID:015245330</ref><ref group="xtra">PMID:012351792</ref><references group="xtra"/>
[[Category: Myxococcus xanthus]]
[[Category: Myxococcus xanthus]]
[[Category: Prolyl oligopeptidase]]
[[Category: Prolyl oligopeptidase]]
Line 29: Line 21:
[[Category: Shan, L.]]
[[Category: Shan, L.]]
[[Category: Celiac sprue]]
[[Category: Celiac sprue]]
[[Category: Crystal structure]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Mechanistic study]]
[[Category: Mechanistic study]]
[[Category: Prolyl endopeptidase]]
[[Category: Prolyl endopeptidase]]
[[Category: Protease]]
[[Category: Protease]]

Revision as of 12:10, 23 January 2013

File:2bkl.png

Template:STRUCTURE 2bkl

STRUCTURAL AND MECHANISTIC ANALYSIS OF TWO PROLYL ENDOPEPTIDASES: ROLE OF INTER-DOMAIN DYNAMICS IN CATALYSIS AND SPECIFICITY

Template:ABSTRACT PUBMED 15738423

About this Structure

2bkl is a 2 chain structure with sequence from Myxococcus xanthus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Shan L, Mathews II, Khosla C. Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3599-604. Epub 2005 Feb 28. PMID:15738423
  2. Shan L, Marti T, Sollid LM, Gray GM, Khosla C. Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue. Biochem J. 2004 Oct 15;383(Pt 2):311-8. PMID:15245330 doi:10.1042/BJ20040907
  3. Shan L, Molberg O, Parrot I, Hausch F, Filiz F, Gray GM, Sollid LM, Khosla C. Structural basis for gluten intolerance in celiac sprue. Science. 2002 Sep 27;297(5590):2275-9. PMID:12351792 doi:10.1126/science.1074129

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