2zal: Difference between revisions

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[[Image:2zal.png|left|200px]]
[[Image:2zal.png|left|200px]]


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{{STRUCTURE_2zal|  PDB=2zal  |  SCENE=  }}  
{{STRUCTURE_2zal|  PDB=2zal  |  SCENE=  }}  


===Crystal structure of E. coli isoaspartyl aminopeptidase/L-asparaginase in complex with L-aspartate===
===Crystal structure of E. coli isoaspartyl aminopeptidase/L-asparaginase in complex with L-aspartate===


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{{ABSTRACT_PUBMED_15946951}}
{{ABSTRACT_PUBMED_15946951}}


==About this Structure==
==About this Structure==
[[2zal]] is a 4 chain structure of [[Aminopeptidase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k12 Escherichia coli k12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1seo 1seo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAL OCA].  
[[2zal]] is a 4 chain structure of [[Aminopeptidase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1seo 1seo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAL OCA].  


==See Also==
==See Also==
*[[Aminopeptidase]]
*[[Aminopeptidase|Aminopeptidase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15946951</ref><ref group="xtra">PMID:11053866</ref><ref group="xtra">PMID:7477383</ref><ref group="xtra">PMID:9541410</ref><ref group="xtra">PMID:8846222</ref><ref group="xtra">PMID:9685368</ref><ref group="xtra">PMID:10490104</ref><ref group="xtra">PMID:14616088</ref><ref group="xtra">PMID:15159592</ref><references group="xtra"/>
<ref group="xtra">PMID:015946951</ref><ref group="xtra">PMID:011053866</ref><ref group="xtra">PMID:007477383</ref><ref group="xtra">PMID:009541410</ref><ref group="xtra">PMID:008846222</ref><ref group="xtra">PMID:009685368</ref><ref group="xtra">PMID:010490104</ref><ref group="xtra">PMID:014616088</ref><ref group="xtra">PMID:015159592</ref><references group="xtra"/>
[[Category: Escherichia coli k12]]
[[Category: Escherichia coli]]
[[Category: Brzezinski, K.]]
[[Category: Brzezinski, K.]]
[[Category: Jaskolski, M.]]
[[Category: Jaskolski, M.]]
Line 32: Line 21:
[[Category: Asparaginase]]
[[Category: Asparaginase]]
[[Category: Autoproteolysis]]
[[Category: Autoproteolysis]]
[[Category: Hydrolase]]
[[Category: Isoaspartyl peptidase]]
[[Category: Isoaspartyl peptidase]]
[[Category: L-aspartate/calcium cluster]]
[[Category: L-aspartate/calcium cluster]]
[[Category: Ntn-hydrolase]]
[[Category: Ntn-hydrolase]]

Revision as of 22:16, 25 July 2012

File:2zal.png

Template:STRUCTURE 2zal

Crystal structure of E. coli isoaspartyl aminopeptidase/L-asparaginase in complex with L-aspartate

Template:ABSTRACT PUBMED 15946951

About this Structure

2zal is a 4 chain structure of Aminopeptidase with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1seo. Full crystallographic information is available from OCA.

See Also

Reference

  1. Michalska K, Brzezinski K, Jaskolski M. Crystal structure of isoaspartyl aminopeptidase in complex with L-aspartate. J Biol Chem. 2005 Aug 5;280(31):28484-91. Epub 2005 Jun 9. PMID:15946951 doi:10.1074/jbc.M504501200
  2. Borek D, Jaskolski M. Crystallization and preliminary crystallographic studies of a new L-asparaginase encoded by the Escherichia coli genome. Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1505-7. PMID:11053866
  3. Brannigan JA, Dodson G, Duggleby HJ, Moody PC, Smith JL, Tomchick DR, Murzin AG. A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature. 1995 Nov 23;378(6555):416-9. PMID:7477383 doi:https://dx.doi.org/10.1038/378416a0
  4. Xuan J, Tarentino AL, Grimwood BG, Plummer TH Jr, Cui T, Guan C, Van Roey P. Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum. Protein Sci. 1998 Mar;7(3):774-81. PMID:9541410
  5. Oinonen C, Tikkanen R, Rouvinen J, Peltonen L. Three-dimensional structure of human lysosomal aspartylglucosaminidase. Nat Struct Biol. 1995 Dec;2(12):1102-8. PMID:8846222
  6. Guo HC, Xu Q, Buckley D, Guan C. Crystal structures of Flavobacterium glycosylasparaginase. An N-terminal nucleophile hydrolase activated by intramolecular proteolysis. J Biol Chem. 1998 Aug 7;273(32):20205-12. PMID:9685368
  7. Xu Q, Buckley D, Guan C, Guo HC. Structural insights into the mechanism of intramolecular proteolysis. Cell. 1999 Sep 3;98(5):651-61. PMID:10490104
  8. Saarela J, Oinonen C, Jalanko A, Rouvinen J, Peltonen L. Autoproteolytic activation of human aspartylglucosaminidase. Biochem J. 2004 Mar 1;378(Pt 2):363-71. PMID:14616088 doi:10.1042/BJ20031496
  9. Prahl A, Pazgier M, Hejazi M, Lockau W, Lubkowski J. Structure of the isoaspartyl peptidase with L-asparaginase activity from Escherichia coli. Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1173-6. Epub 2004, May 21. PMID:15159592 doi:10.1107/S0907444904003403

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