3f1a: Difference between revisions
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[[Image:3f1a.png|left|200px]] | [[Image:3f1a.png|left|200px]] | ||
{{STRUCTURE_3f1a| PDB=3f1a | SCENE= }} | {{STRUCTURE_3f1a| PDB=3f1a | SCENE= }} | ||
===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)benzenesulfonamide=== | ===Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)benzenesulfonamide=== | ||
{{ABSTRACT_PUBMED_17269766}} | {{ABSTRACT_PUBMED_17269766}} | ||
==About this Structure== | ==About this Structure== | ||
[[3f1a]] is a 1 chain structure of [[Elastase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1A OCA]. | [[3f1a]] is a 1 chain structure of [[Elastase]] and [[Matrix metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F1A OCA]. | ||
==See Also== | ==See Also== | ||
*[[Elastase]] | *[[Elastase|Elastase]] | ||
*[[Matrix metalloproteinase|Matrix metalloproteinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017269766</ref><ref group="xtra">PMID:012813751</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
[[Category: Calderone, V.]] | [[Category: Calderone, V.]] | ||
[[Category: Elastase]] | [[Category: Elastase]] | ||
[[Category: Extracellular matrix]] | [[Category: Extracellular matrix]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Mmp12]] | [[Category: Mmp12]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 02:39, 27 July 2012
Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor N-(2-nitroso-2-oxoethyl)benzenesulfonamide
Template:ABSTRACT PUBMED 17269766
About this Structure
3f1a is a 1 chain structure of Elastase and Matrix metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bertini I, Calderone V, Fragai M, Giachetti A, Loconte M, Luchinat C, Maletta M, Nativi C, Yeo KJ. Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. J Am Chem Soc. 2007 Mar 7;129(9):2466-75. Epub 2007 Feb 2. PMID:17269766 doi:10.1021/ja065156z
- Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B. X-ray structures of binary and ternary enzyme-product-inhibitor complexes of matrix metalloproteinases. Angew Chem Int Ed Engl. 2003 Jun 16;42(23):2673-6. PMID:12813751 doi:10.1002/anie.200350957
