3bvb: Difference between revisions

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[[Image:3bvb.png|left|200px]]
[[Image:3bvb.png|left|200px]]


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{{STRUCTURE_3bvb|  PDB=3bvb  |  SCENE=  }}  
{{STRUCTURE_3bvb|  PDB=3bvb  |  SCENE=  }}  


===Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir===
===Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir===


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{{ABSTRACT_PUBMED_18281688}}
{{ABSTRACT_PUBMED_18281688}}


==About this Structure==
==About this Structure==
[[3bvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVB OCA].  
[[3bvb]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BVB OCA].  
 
==See Also==
*[[Virus protease|Virus protease]]


==Reference==
==Reference==
<ref group="xtra">PMID:18281688</ref><ref group="xtra">PMID:12933791</ref><ref group="xtra">PMID:16277992</ref><references group="xtra"/>
<ref group="xtra">PMID:018281688</ref><ref group="xtra">PMID:012933791</ref><ref group="xtra">PMID:016277992</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Capsid maturation]]
[[Category: Capsid maturation]]
[[Category: Core protein]]
[[Category: Core protein]]
[[Category: Cytoplasm]]
[[Category: D25n]]
[[Category: D25n]]
[[Category: Dna integration]]
[[Category: Dna integration]]
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[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 13:02, 26 July 2012

File:3bvb.png

Template:STRUCTURE 3bvb

Cystal structure of HIV-1 Active Site Mutant D25N and inhibitor Darunavir

Template:ABSTRACT PUBMED 18281688

About this Structure

3bvb is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sayer JM, Liu F, Ishima R, Weber IT, Louis JM. Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease. J Biol Chem. 2008 May 9;283(19):13459-70. Epub 2008 Feb 15. PMID:18281688 doi:10.1074/jbc.M708506200
  2. Ishima R, Torchia DA, Lynch SM, Gronenborn AM, Louis JM. Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem. 2003 Oct 31;278(44):43311-9. Epub 2003 Aug 21. PMID:12933791 doi:https://dx.doi.org/10.1074/jbc.M307549200
  3. Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT. Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992 doi:10.1016/j.jmb.2005.09.095

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