3mz8: Difference between revisions
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{{STRUCTURE_3mz8| PDB=3mz8 | SCENE= }} | {{STRUCTURE_3mz8| PDB=3mz8 | SCENE= }} | ||
===Crystal Structure of Zinc-Bound Natrin From Naja atra=== | ===Crystal Structure of Zinc-Bound Natrin From Naja atra=== | ||
{{ABSTRACT_PUBMED_20889969}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CRVP1_NAJAT CRVP1_NAJAT]] Inhibits calcium-activated potassium channels (KCa1.1/KCNMA1), voltage-gated potassium channel Kv1.3/KCNA3, and the calcium release channel/ryanodine receptor (RyR). Binds specifically to type 1 RyR (RyR1) from skeletal muscle. Inhibit both the binding of ryanodine to RyR1, and RyR1's calcium-channel activity. Inhibits carbachol-induced muscle contraction and weakly blocks muscle contraction evoked by potassium.<ref>PMID:15581679</ref> <ref>PMID:17070778</ref> <ref>PMID:18658224</ref> <ref>PMID:16042391</ref> | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020889969</ref><ref group="xtra">PMID:015388950</ref><references group="xtra"/><references/> | ||
[[Category: Naja atra]] | [[Category: Naja atra]] | ||
[[Category: Chen, C J.]] | [[Category: Chen, C J.]] | ||