2qx1: Difference between revisions
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[[Image:2qx1.png|left|200px]] | [[Image:2qx1.png|left|200px]] | ||
{{STRUCTURE_2qx1| PDB=2qx1 | SCENE= }} | {{STRUCTURE_2qx1| PDB=2qx1 | SCENE= }} | ||
===Crystal structure of the complex between mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FABH) and decyl-COA disulfide=== | ===Crystal structure of the complex between mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FABH) and decyl-COA disulfide=== | ||
{{ABSTRACT_PUBMED_18096200}} | {{ABSTRACT_PUBMED_18096200}} | ||
==About this Structure== | ==About this Structure== | ||
[[2qx1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QX1 OCA]. | [[2qx1]] is a 2 chain structure of [[Acyl carrier protein synthase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QX1 OCA]. | ||
==See Also== | |||
*[[Acyl carrier protein synthase|Acyl carrier protein synthase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018096200</ref><ref group="xtra">PMID:011278743</ref><ref group="xtra">PMID:015713483</ref><references group="xtra"/> | ||
[[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | [[Category: Beta-ketoacyl-acyl-carrier-protein synthase I]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| Line 32: | Line 24: | ||
[[Category: Wright, H T.]] | [[Category: Wright, H T.]] | ||
[[Category: Acyltransferase]] | [[Category: Acyltransferase]] | ||
[[Category: Enzyme inhibitor complex]] | [[Category: Enzyme inhibitor complex]] | ||
[[Category: Fatty acid biosynthesis]] | [[Category: Fatty acid biosynthesis]] | ||
Revision as of 16:35, 26 July 2012
Crystal structure of the complex between mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FABH) and decyl-COA disulfide
Template:ABSTRACT PUBMED 18096200
About this Structure
2qx1 is a 2 chain structure of Acyl carrier protein synthase with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Sachdeva S, Musayev F, Alhamadsheh MM, Neel Scarsdale J, Tonie Wright H, Reynolds KA. Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorg Chem. 2008 Apr;36(2):85-90. Epub 2007 Dec 21. PMID:18096200 doi:10.1016/j.bioorg.2007.11.001
- Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT. Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8. PMID:11278743 doi:10.1074/jbc.M010762200
- Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PMID:15713483 doi:10.1016/j.jmb.2004.12.044
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Beta-ketoacyl-acyl-carrier-protein synthase I
- Mycobacterium tuberculosis
- Alhamadsheh, M.
- Musayev, F.
- Reynolds, K A.
- Sachdeva, S.
- Scarsdale, J N.
- Wright, H T.
- Acyltransferase
- Enzyme inhibitor complex
- Fatty acid biosynthesis
- Lipid synthesis
- Mechanism based inhibitor
- Multifunctional enzyme
- Myobacterium tuberculosis
- Structural basis for substrate specificity
- Transferase
