3fr0: Difference between revisions
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[[Image:3fr0.png|left|200px]] | [[Image:3fr0.png|left|200px]] | ||
{{STRUCTURE_3fr0| PDB=3fr0 | SCENE= }} | {{STRUCTURE_3fr0| PDB=3fr0 | SCENE= }} | ||
===Human glucokinase in complex with 2-amino benzamide activator=== | ===Human glucokinase in complex with 2-amino benzamide activator=== | ||
{{ABSTRACT_PUBMED_19188063}} | {{ABSTRACT_PUBMED_19188063}} | ||
==About this Structure== | ==About this Structure== | ||
[[3fr0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR0 OCA]. | [[3fr0]] is a 1 chain structure of [[Hexokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR0 OCA]. | ||
==See Also== | |||
*[[Hexokinase|Hexokinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019188063</ref><ref group="xtra">PMID:015016359</ref><references group="xtra"/> | ||
[[Category: Glucokinase]] | [[Category: Glucokinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kamata, K.]] | [[Category: Kamata, K.]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Diabetes]] | [[Category: Diabetes]] | ||
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[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 23:18, 25 July 2012
Human glucokinase in complex with 2-amino benzamide activator
Template:ABSTRACT PUBMED 19188063
About this Structure
3fr0 is a 1 chain structure of Hexokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Nishimura T, Iino T, Mitsuya M, Bamba M, Watanabe H, Tsukahara D, Kamata K, Sasaki K, Ohyama S, Hosaka H, Futamura M, Nagata Y, Eiki J. Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1357-60. Epub 2009 Jan 21. PMID:19188063 doi:10.1016/j.bmcl.2009.01.053
- Kamata K, Mitsuya M, Nishimura T, Eiki J, Nagata Y. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase. Structure. 2004 Mar;12(3):429-38. PMID:15016359 doi:10.1016/j.str.2004.02.005