2xpk: Difference between revisions

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[[Image:2xpk.jpg|left|200px]]
[[Image:2xpk.png|left|200px]]


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{{STRUCTURE_2xpk|  PDB=2xpk  |  SCENE=  }}  
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===CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES===
===CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES===


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{{ABSTRACT_PUBMED_21095575}}


==About this Structure==
==About this Structure==
[[2xpk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPK OCA].  
[[2xpk]] is a 2 chain structure of [[Beta-Hexosaminidase]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XPK OCA].  
 
==See Also==
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]


==Reference==
==Reference==
<ref group="xtra">PMID:21095575</ref><references group="xtra"/>
<ref group="xtra">PMID:021095575</ref><references group="xtra"/>
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Clostridium perfringens]]
[[Category: Clostridium perfringens]]
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[[Category: Schimpl, M.]]
[[Category: Schimpl, M.]]
[[Category: Zheng, X.]]
[[Category: Zheng, X.]]
[[Category: Hydrolase]]
[[Category: Signalling]]

Revision as of 13:26, 25 July 2012

File:2xpk.png

Template:STRUCTURE 2xpk

CELL-PENETRANT, NANOMOLAR O-GLCNACASE INHIBITORS SELECTIVE AGAINST LYSOSOMAL HEXOSAMINIDASES

Template:ABSTRACT PUBMED 21095575

About this Structure

2xpk is a 2 chain structure of Beta-Hexosaminidase with sequence from Clostridium perfringens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Dorfmueller HC, Borodkin VS, Schimpl M, Zheng X, Kime R, Read KD, van Aalten DM. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases. Chem Biol. 2010 Nov 24;17(11):1250-5. PMID:21095575 doi:10.1016/j.chembiol.2010.09.014

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