Agrin: Difference between revisions
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[[Image:3i70.jpg|left|200px|thumb|Crystal Structure of chicken Agrin, [[3i70]]]] | [[Image:3i70.jpg|left|200px|thumb|Crystal Structure of chicken Agrin, [[3i70]]]] | ||
{{STRUCTURE_3i70| PDB=3i70 | SIZE= | {{STRUCTURE_3i70| PDB=3i70 | SIZE=400| SCENE=Agrin/Cv/1 |right|CAPTION=chicken Agrin, [[3i70]] }} | ||
[[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | [[Agrin]] (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, ''i.e.'' the crystal structure of chicken Agrin ([[3i70]]). | ||
Revision as of 11:05, 22 March 2012
Agrin (Agr) is involved in the embryogenesis of the neuromuscular junction. It is involved in the aggregation of acetylcholine receptors. Its N-terminal domain NtA binds laminin. The C-terminal of Agr has 3 laminin binding domains (LMB): G1-G3. The images at the left and at the right correspond to one representative Agrin, i.e. the crystal structure of chicken Agrin (3i70).
3D Structures of Agrin
3i70, 1pxu – cNtA – chicken
1pz7, 1pz8, 1pz9 – cAgr
1q56 – cAgr-G3+Ca – NMR
1jb3, 1jc7 – cAgr LMB
3pve – Agr G2 - mouse
