3kba: Difference between revisions
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m Protected "3kba" [edit=sysop:move=sysop] |
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{{STRUCTURE_3kba| PDB=3kba | SCENE= }} | {{STRUCTURE_3kba| PDB=3kba | SCENE= }} | ||
===Progesterone receptor bound to sulfonamide pyrrolidine partial agonist=== | ===Progesterone receptor bound to sulfonamide pyrrolidine partial agonist=== | ||
{{ABSTRACT_PUBMED_19926282}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PRGR_HUMAN PRGR_HUMAN]] The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.<ref>PMID:15572662</ref> <ref>PMID:15798179</ref> <ref>PMID:17020914</ref> <ref>PMID:17347654</ref> <ref>PMID:17717077</ref> <ref>PMID:17173941</ref> <ref>PMID:18202149</ref> Isoform A is inactive in stimulating c-Src/MAPK signaling on hormone stimulation.<ref>PMID:15572662</ref> <ref>PMID:15798179</ref> <ref>PMID:17020914</ref> <ref>PMID:17347654</ref> <ref>PMID:17717077</ref> <ref>PMID:17173941</ref> <ref>PMID:18202149</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019926282</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kallander, L S.]] | [[Category: Kallander, L S.]] | ||
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[[Category: Washburn, D G.]] | [[Category: Washburn, D G.]] | ||
[[Category: Williams, S P.]] | [[Category: Williams, S P.]] | ||
[[Category: Nuclear receptor]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription regulation]] | |||