3n51: Difference between revisions

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[[Image:3n51.png|left|200px]]
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{{STRUCTURE_3n51|  PDB=3n51  |  SCENE=  }}  
{{STRUCTURE_3n51|  PDB=3n51  |  SCENE=  }}  
===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor RM-1-95===
===Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor RM-1-95===
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{{ABSTRACT_PUBMED_21116453}}
{{ABSTRACT_PUBMED_21116453}}


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==Reference==
==Reference==
<ref group="xtra">PMID:21116453</ref><ref group="xtra">PMID:20436472</ref><references group="xtra"/>
<ref group="xtra">PMID:021116453</ref><ref group="xtra">PMID:020436472</ref><references group="xtra"/><references/>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Toxoplasma gondii]]
[[Category: Toxoplasma gondii]]
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[[Category: MSGPP, Medical Structural Genomics of Pathogenic Protozoa.]]
[[Category: MSGPP, Medical Structural Genomics of Pathogenic Protozoa.]]
[[Category: Merritt, E A.]]
[[Category: Merritt, E A.]]
[[Category: Atp-binding]]
[[Category: Bumped kinase inhibitor]]
[[Category: Calcium-binding]]
[[Category: Calmodulin]]
[[Category: Medical structural genomics of pathogenic protozoa]]
[[Category: Msgpp]]
[[Category: Serine/threonine protein kinase]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 21:10, 17 April 2013

Template:STRUCTURE 3n51

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor RM-1-95

Template:ABSTRACT PUBMED 21116453

About this Structure

3n51 is a 1 chain structure with sequence from Toxoplasma gondii. Full crystallographic information is available from OCA.

Reference

  1. Murphy RC, Ojo KK, Larson ET, Castellanos-Gonzalez A, Perera BG, Keyloun KR, Kim JE, Bhandari JG, Muller NR, Verlinde CL, White AC, Merritt EA, Van Voorhis WC, Maly DJ. Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. ACS Med Chem Lett. 2010 Oct 14;1(7):331-335. PMID:21116453 doi:10.1021/ml100096t
  2. Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, Derocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, Napuli AJ, Maly DJ, Verlinde CL, Buckner FS, Parsons M, Hol WG, Merritt EA, Van Voorhis WC. Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol. 2010 May;17(5):602-7. Epub 2010 May 2. PMID:20436472 doi:10.1038/nsmb.1818

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