3m1h: Difference between revisions
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m Protected "3m1h" [edit=sysop:move=sysop] |
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{{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | {{STRUCTURE_3m1h| PDB=3m1h | SCENE= }} | ||
===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ===Crystal Structure Analysis of the K3 Cleaved Adhesin Domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis w83=== | ||
{{ABSTRACT_PUBMED_021812842}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/O52050_PORGI O52050_PORGI]] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2] | |||
==About this Structure== | ==About this Structure== | ||
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[[Category: Hunter, N.]] | [[Category: Hunter, N.]] | ||
[[Category: Li, N.]] | [[Category: Li, N.]] | ||
[[Category: Beta jelly roll barrel]] | |||
[[Category: Carbohydrate binding]] | |||
[[Category: Cell invasion]] | |||
[[Category: Cleaved adhesin family]] | |||
[[Category: Hemagglutination domain]] | |||
[[Category: Lys-gingipain]] | |||
[[Category: Protease]] | |||