Prion: Difference between revisions
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[[Image:3haf.png|left|200px|thumb|Crystal Structure of human prion [[3haf]]]] | [[Image:3haf.png|left|200px|thumb|Crystal Structure of human prion [[3haf]]]] | ||
{{STRUCTURE_3haf| PDB=3haf | SIZE=300| SCENE= |right|CAPTION=human prion [[3haf]] }} | {{STRUCTURE_3haf| PDB=3haf | SIZE=300| SCENE=Prion/Cv/1 |right|CAPTION=human prion [[3haf]] }} | ||
'''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[2haf]]). | '''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[2haf]]). | ||
