Sandbox Reserved 168: Difference between revisions
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== SKI protein == | == SKI protein == | ||
<Structure load='1sbx' size='500' frame='true' align='right' caption=' | <Structure load='1sbx' size='500' frame='true' align='right' caption='Crystal Structure of human SKI, PDB ID: 1SBX' scene='Insert optional scene name here' /><!-- PLEASE DO NOT DELETE THIS TEMPLATE --> | ||
{{Sandbox_Reserved_Irma_Santoro_7}} | {{Sandbox_Reserved_Irma_Santoro_7}} | ||
<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | <!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
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== Background == | == Background == | ||
A proto-oncoprotein is a gene that can become an oncogene, or a gene that has the potential to cause cancer if mutated or if expressed in quantitative amounts. The SKI protein acts as said protooncogene. Although The SKI protein has been associated with tumors at large levels of cellular concentrations and it has been shown to interfere with normal cellular functioning. | A proto-oncoprotein is a gene that can become an oncogene, or a gene that has the potential to cause cancer if mutated or if expressed in quantitative amounts. The SKI protein acts as said protooncogene. Although The SKI protein has been associated with tumors at large levels of cellular concentrations and it has been shown to interfere with normal cellular functioning. | ||
<ref name="SKI protein"> Reed JA, Lin Q, Chen D, Mian IS, Medrano EE. SKI Pathways Inducing Progression of Human Melanoma. June 2005. http://www.ncbi.nlm.nih.gov/pubmed/15986136</ref>. | <ref name="SKI protein"> Reed JA, Lin Q, Chen D, Mian IS, Medrano EE. SKI Pathways Inducing Progression of Human Melanoma. June 2005. http://www.ncbi.nlm.nih.gov/pubmed/15986136</ref>. | ||
== Structure == | == Structure == | ||
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<references /> | <references /> | ||
