3qmc: Difference between revisions

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[[Image:3qmc.png|left|200px]]
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{{STRUCTURE_3qmc|  PDB=3qmc  |  SCENE=  }}  
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===Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1===
===Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1===
{{ABSTRACT_PUBMED_21407193}}


 
==Function==
<!--
[[http://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN]] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref>
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{{ABSTRACT_PUBMED_21407193}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21407193</ref><references group="xtra"/>
<ref group="xtra">PMID:021407193</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
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[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Xu, C.]]
[[Category: Xu, C.]]
[[Category: Cxxc-type zn finger]]
[[Category: Dna binding]]
[[Category: Dna binding protein-dna complex]]
[[Category: Nucleus speckle]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Unmethylated cpg motif]]

Revision as of 08:26, 8 May 2013

Template:STRUCTURE 3qmc

Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1

Template:ABSTRACT PUBMED 21407193

Function

[CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.[1]

About this Structure

3qmc is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237
  1. ↑ Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237

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