3r4b: Difference between revisions
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[[Image:3r4b.jpg|left|200px]] | |||
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{{STRUCTURE_3r4b| PDB=3r4b | SCENE= }} | |||
===Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911=== | |||
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{{ABSTRACT_PUBMED_21896904}} | |||
==About this Structure== | |||
[[3r4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R4B OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021896904</ref><references group="xtra"/> | |||
[[Category: Human immunodeficiency virus 1]] | |||
[[Category: Nalam, M N.L.]] | |||
[[Category: Schiffer, C A.]] | |||
[[Category: Aid]] | |||
[[Category: Aspartyl protease]] | |||
[[Category: Drug design]] | |||
[[Category: Drug resistance]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Protease inhibitor]] | |||
Revision as of 05:55, 21 September 2011
Crystal Structure of Wild-type HIV-1 Protease in Complex With TMC310911
Template:ABSTRACT PUBMED 21896904
About this Structure
3r4b is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Dierynck I, Van Marck H, Van Ginderen M, Jonckers TH, Nalam MN, Schiffer CA, Raoof A, Kraus G, Picchio G. TMC310911, a Novel Human Immunodeficiency Virus Type-1 Protease Inhibitor shows in Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors. Antimicrob Agents Chemother. 2011 Sep 6. PMID:21896904 doi:10.1128/AAC.00748-11
