Sandbox Reserved 321: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 21: | Line 21: | ||
=Structure of InhA= | =Structure of InhA= | ||
The inhA enzyme of ''M. tuberculosis'' is a homotetramer composed of a repeating subunit comprised of a single domain with a [http://en.wikipedia.org/wiki/Rossmann_fold Rossmann Fold] in the core that provides a NADH binding site<ref name ="crystallographic studies"/>. The single domain can be broken down into two substructures that are connected by short peptide loop<ref name ="making drugs for inhA"/><ref name ="crystallographic studies">PMID:17588773</ref>. | The inhA enzyme <scene name='Sandbox_Reserved_321/Structural_progression_1/1'>(go to original orientation)</scene> of ''M. tuberculosis'' is a homotetramer composed of a repeating subunit comprised of a single domain with a [http://en.wikipedia.org/wiki/Rossmann_fold Rossmann Fold] in the core that provides a NADH binding site<ref name ="crystallographic studies"/>. The single domain can be broken down into two substructures that are connected by short peptide loop<ref name ="making drugs for inhA"/><ref name ="crystallographic studies">PMID:17588773</ref>. | ||
<Structure load='2h9i' size='250' frame='true' align='left' caption='Momomeric subunit of inhA' scene='Sandbox_Reserved_321/Structural_progresion/1' /> | <Structure load='2h9i' size='250' frame='true' align='left' caption='Momomeric subunit of inhA' scene='Sandbox_Reserved_321/Structural_progresion/1' /> | ||
