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== Introduction ==
== Introduction ==


[http://en.wikipedia.org/wiki/Cytochrome Cytochromes] are a class of heme-containing proteins that are generally membrane-bound. They are soluble proteins<ref name=main /> found in bacteria and the mitochondria of eukaryotic organisms, and are known as respiratory pigments because they are involved in electron transfer in various electron transport chains.<ref name="heme">PMID:14871137</ref> Cytochromes can be categorized into three different types, all based on the type of prosthetic heme group the cytochrome contains. Cytochrome ''c'' is named such because it contains the heme ''c'', which is distinguished from hemes ''a'', ''b'', and ''d'' by its coordination to the protein scaffold by cysteinyl residues.<ref name=heme />  
[http://en.wikipedia.org/wiki/Cytochrome Cytochromes] are a class of heme-containing proteins found in bacteria and the mitochondria of eukaryotes.<ref name=main /> These proteins are generally membrane-bound and are known as respiratory pigments because they are involved in various electron transport systems in oxidative phosphorylation.<ref name="heme">PMID:14871137</ref> Cytochromes can be categorized into several different types, three of which are based on the type of prosthetic heme group the cytochrome contains: cytochromes ''a'' contains heme ''a'', cyt ''b'' contains heme ''b'', and cyt ''d'' containing a tetrapyrrolic chelate of iron.<ref name="cytd">http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&term=Cytochrome+d MeSH</ref> Cytochrome ''c'' is named such because it contains the heme ''c'', which is distinguished from hemes ''a'', ''b'', and ''d'' by its coordination to the protein scaffold by cysteinyl residues to either one or both of the heme's vinyl side chains<ref name=heme />  


Cyt ''c'' has been split into four classes<ref name=”amb”>PMID:1646017</ref>, Class I containing single domain C-type cytochromes of which there has been at least six classes found in prokaryotes such as [http://en.wikipedia.org/wiki/Desulfovibrio ''Desulfovibrio desulfuricans''], [http://en.wikipedia.org/wiki/Rhodospirillum_rubrum ''Rhodospirillum rubrum''], and ''Rhodothermus marinus''.  
Cyt ''c'' has been split into four classes.<ref name=”amb”>PMID:1646017</ref> Class I contains single domain C-type cytochromes, of which there has been at least six subclasses found in prokaryotes including [http://en.wikipedia.org/wiki/Desulfovibrio ''Desulfovibrio desulfuricans''], [http://en.wikipedia.org/wiki/Rhodospirillum_rubrum ''Rhodospirillum rubrum''], and ''Rhodothermus marinus''. Class II cyt ''c'' contains
   
   
=== ''Rhodothermus marinus'' ===
=== ''Rhodothermus marinus'' ===