Sandbox Reserved 350: Difference between revisions
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Coagulation Factor V studied in 1987 by William H. Kane, Akitada Ichinose, Frederick S. Hagen and Earl W. Davie, out of University of Washington, Seattle <ref name="Old">PMID: 2827731 </ref> | Coagulation Factor V studied in 1987 by William H. Kane, Akitada Ichinose, Frederick S. Hagen and Earl W. Davie, out of University of Washington, Seattle <ref name="Old">PMID: 2827731 </ref> | ||
{{STRUCTURE_1czv|PDB=1czv|SCENE=}} | {{STRUCTURE_1czv|PDB=1czv|SCENE=}} | ||
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FVa consists of a conserved '''<font color='red'> β-Barrel framework </font> ''' acting as a scaffold for <font color='orangered'> '''three loops''' </font> of the '''C2 domain''' (FVa-C2).<ref name="Pubmed"/> | FVa consists of a conserved '''<font color='red'> β-Barrel framework </font> ''' acting as a scaffold for <font color='orangered'> '''three loops''' </font> of the '''C2 domain''' (FVa-C2).<ref name="Pubmed"/> | ||
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[[Image:3D Jellow B-Barrel Motif.png|thumb|left|upright=1.5|alt=Distorted Jelly-Roll β-barrel motif with three active loops. The β-barrel motif is labeled in red and the three loops in orange.|Secondary structure of C2 Domain of 1czv.]] | |||
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'''The FVa-C2''', which is classified as a ''' <font color='red'> distorted jelly-roll </font> β-barrel motif''', which is compossed of '''eight major antiparallel strands''' arranged into two ''' <font color='green'> β-sheets of five </font> and <font color='olive'> three strands </font> ''' packed against one another. | '''The FVa-C2''', which is classified as a ''' <font color='red'> distorted jelly-roll </font> β-barrel motif''', which is compossed of '''eight major antiparallel strands''' arranged into two ''' <font color='green'> β-sheets of five </font> and <font color='olive'> three strands </font> ''' packed against one another. | ||
